| ORIGINAL ARTICLE |
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| Year : 2015 | Volume
: 18
| Issue : 3 | Page : 192-195 |
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The effect of two types chewing gum containing casein phosphopeptide-amorphous calcium phosphate and xylitol on salivary Streptococcus mutans
Shila Emamieh1, Yosra Khaterizadeh1, Hossein Goudarzi2, Amir Ghasemi3, Alireza Akbarzadeh Baghban4, Hasan Torabzadeh3
1 Department of Operative Dentistry, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran
2 Department of Clinical Microbiology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
3 Iranian Center for Endodontic Research, Shahid Beheshti University of Medical Sciences, Tehran, Iran
4 Department of Basic Sciences, School of Rehabilitation, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Correspondence Address:
Dr. Shila Emamieh
Department of Operative Dentistry, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran
Iran
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/0972-0707.157240
Clinical trial registration IRCT2014063018296N1
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Aim: The aim was to evaluate the effect of sugar-free chewing gum containing casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) and xylitol on salivary Streptococcus mutans.
Materials and Methods: A total of 60 dental students of 20-25 years old, who volunteered after checking their health condition and signing an informed consent, were randomly allocated to receive one of the following interventions: (A) Chewing gum containing CPP-ACP; (B) containing xylitol. Subjects within the experimental groups were taken the gums 3 times daily, after each meal for a period of 3 weeks. Pre- and post-intervention unstimulated saliva samples were quantified for S. mutans counts.
Results: A statistically significant reduction of salivary S. mutans was displayed in both groups A and B after the intervention when compared with baseline (P < 0.001), and group A shows more statistically significant reduction of salivary S. mutans than group B (P = 0.011).
Conclusion: Daily consumption of chewing gum containing CPP-ACP and xylitol significantly reduces the level of salivary S. mutans, but chewing gum containing CPP-ACP can reduce the level of salivary S. mutans in more than xylitol chewing gum. |
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