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ORIGINAL ARTICLE
Year : 2015  |  Volume : 18  |  Issue : 2  |  Page : 128-131

Comparative evaluation of antimicrobial efficacy of QMix TM 2 in 1, sodium hypochlorite, and chlorhexidine against Enterococcus faecalis and Candida albicans


1 Department of Conservative Dentistry and Endodontics, Mamata Dental College, Khammam, Andhra Pradesh, India
2 Department of Oral Pathology and Microbiology, Mamata Dental College, Khammam, Andhra Pradesh, India

Correspondence Address:
Dr. Veeramachaneni Chandrasekhar
Department of Conservative Dentistry and Endodontics, Mamata Dental College, Khammam - 507 002, Andhra Pradesh
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0972-0707.153067

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Aim/Objective: The aim of this study is to compare the antimicrobial efficacy of QMix TM 2 in 1, sodium hypochlorite (NaOCl), and chlorhexidine (CHX) against Enterococcus faecalis and Candida albicans. Materials and Methods: Eighty freshly extracted, single-rooted human mandibular premolar teeth were instrumented and autoclaved. Samples were divided into two groups of 40 teeth each based on the type of microorganism used. Group I was inoculated with E. faecalis and Group II with C. albicans and incubated for 3 days. Each group was subdivided into four subgroups based on the type of irrigant used. Group IA, IIA, 5.25% NaOCl; Group IB, IIB, 2% CHX; Group IC, IIC, QMix TM 2 in 1; and Group ID, IID, 0.9% saline (the control group). Ten microliters of the sample from each canal was taken and was placed on Brain Heart Infusion agar and Sabouraud dextrose agar. The plates were incubated at 37°C for 24 h and colony forming units (CFUs) that were grown were counted. Data was analyzed with analysis of variance (ANOVA) followed by post-hoc Games-Howell test. Results: The greatest antimicrobial effects were observed in samples treated with QMix TM 2 in 1 (P < 0.001). No statistical significant difference was found between 5.25% NaOCl and 2% CHX (P > 0.001) against E. faecalis and C. albicans. Conclusion: QMix TM 2 in 1 demonstrated significant antimicrobial efficacy against E. faecalis and C. albicans.


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