| ORIGINAL ARTICLE |
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| Year : 2014 | Volume
: 17
| Issue : 6 | Page : 517-521 |
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Effect of single dose pretreatment analgesia with three different analgesics on postoperative endodontic pain: A randomized clinical trial
Priyank Sethi, Manish Agarwal, Hemant Ramesh Chourasia, Mahesh Pratap Singh
Department of Conservative Dentistry and Endodontics, Peoples College of Dental Sciences and Research Centre, Bhopal, Madhya Pradesh, India
Correspondence Address:
Priyank Sethi
Department of Conservative Dentistry and Endodontics, Peoples College of Dental Sciences and Research Centre, Bhopal - 462 037, Madhya Pradesh
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/0972-0707.144574
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Introduction: One of the aims of root canal treatment is to prevent or eliminate pain. Postoperative endodontic pain control continues to be a significant challenge.
Aim: To compare and evaluate the effect of single oral dose of 100 mg of tapentadol, 400 mg of etodolac, or 10 mg of ketorolac as a pretreatment analgesic for the prevention and control of postoperative endodontic pain in patients with symptomatic irreversible pulpitis. The incidence of side effects was recorded as secondary outcome.
Materials and Methods: Sixty emergency patients with moderate to severe pain, diagnosed with symptomatic irreversible pulpitis were randomly allocated (1:1:1) to any of the three groups; tapentadol, etodolac, or ketorolac. Medications were administered 30 min before beginning of the endodontic treatment. Patients recorded pain intensity on 10 cm visual analog scale (VAS) after treatment, for upto 24 h.
Results: At 24 h, mean ±standard deviation (SD) of VAS scores (in cm) for tapentadol, etodolac, and ketorolac were 0.89 ± 0.83, 2.68 ± 2.29, and 0.42 ± 0.69, respectively. Kruskal-Wallis (K-W) test showed significant difference among the three groups (P = 0.001). Mann-Whitney test showed significantly lower VAS scores in tapentadol and ketorolac than etodolac group (P = 0.013 and 0.001, respectively).
Conclusions: Single oral dose of 10 mg of ketorolac and 100mg of tapentadol as a pretreatment analgesic significantly reduced postoperative endodontic pain in patients with symptomatic irreversible pulpitis when compared to 400 mg of etodolac. |
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