| ORIGINAL ARTICLE |
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| Year : 2013 | Volume
: 16
| Issue : 4 | Page : 327-330 |
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Comparative antimicrobial efficacy of Metapex, Metronidazole, BioPure MTAD, Aztreonam on Bacteroides fragilis and Propionibacterium acne
Rajkumar Balakrishnan1, Sandeep Dubey1, Tapan Kumar N Dhole2, Lalit C Boruah1, Sanjeev Srivastava3
1 Department of Conservative Dentistry and Endodontics, Babu Banarasi Das College of Dental Sciences, Lucknow, Uttar Pradesh, India
2 Department of Microbiology, Sanjay Gandhi Postgraduate Institute of Medical Science, Lucknow, Uttar Pradesh, India
3 Department of conservative dentistry and Endodontics, Saraswati Dental College, Lucknow, Uttar Pradesh, India
Correspondence Address:
Sandeep Dubey
Department of Conservative Dentistry and Endodontics, Babu Banarasi Das College of Dental Sciences, Babu Banarasi Das City, Faizabad Road, Lucknow - 227 015, Uttar Pradesh
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/0972-0707.114361
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Aim: The purpose of this study was to evaluate the comparative antibacterial efficacy of Biopure MTAD, Metapex, Metronidazole, and Aztreonam against two obligate anerobic bacteria.
Materials and Methods: Antimicrobial efficacy of selected medicaments against two obligate anaerobic bacteria Bacteroides fragilis and Propionibacterium acnes was done by Agar disc-diffusion method. Pre-sterilized Whatman paper discs, 6 mm in diameter and soaked with the test solution, were prepared and placed onto the previously seeded agar Petri plates. Each plate was incubated in anaerobic jar for anerobic environment at 37°C for 48 hours. A zone of inhibition was recorded for each plate and the results were analysed statistically. Saline and ethanol used as control group in this study.
Results: Biopure MTAD, Metapex and Metronidazole were effective against all the selected microorganisms. Aztreonam was effective against Bacteroides fragilis. Saline and ethanol used as control were ineffective.
Conclusions: Metronidazole showed the superior antibacterial property amongst the tested medicaments. |
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