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Ozone (O3) is an energized form of oxygen. It plays an important role in preserving the atmospheric balance in nature. Ozone production in the upper atmosphere in nature is dependent on the amount of energy coming from the sun. It has been a concern for environmentalists regarding ozone hole and its effect on earth and living beings. Ozone has been used extensively in medical profession and now is gaining a strong foothold in dental profession and is regarded as miraculous cure for the pandemic disease - dental caries. Ozone therapy is also utilized in other aspects of dentistry.