Journal of Conservative Dentistry

ORIGINAL ARTICLE
Year
: 2016  |  Volume : 19  |  Issue : 6  |  Page : 536--540

Histological evaluation of mineral trioxide aggregate and enamel matrix derivative combination in direct pulp capping: An in vivo study


Indira Priyadarshini Bollu1, L Deepa Velagula2, Nagesh Bolla3, K Kiran Kumar4, Archana Hari5, Jayaprakash Thumu1 
1 Department of Conservative Dentistry and Endodontics, St. Joseph Dental College and Hospital, Eluru, Andhra Pradesh, India
2 Department of Conservative Dentistry and Endodontics, Lenora Institute of Dental Sciences, Rajahmundry, Andhra Pradesh, India
3 Department of Conservative Dentistry and Endodontics, Sibar Institute of Dental Sciences, Guntur, Andhra Pradesh, India
4 Department of Oral and Maxillofacial Pathology, Sibar Institute of Dental Sciences, Guntur, Andhra Pradesh, India
5 Department of Periodontics, St. Joseph Dental College and Hospital, Eluru, Andhra Pradesh, India

Correspondence Address:
Dr. Indira Priyadarshini Bollu
Department of Conservative Dentistry and Endodontics, St. Joseph Dental College, Duggirala, Eluru, West Godavari - 534 003, Andhra Pradesh
India

Aim: The aim of this study is to evaluate the response of human pulp tissue to mineral trioxide aggregate (MTA), Emdogain (EMD), and combination of MTA/EMD. Materials and Methods: This study was performed on sixty intact first and second premolars of human maxillary and mandibular teeth. A standard pulpal exposure was done on all the teeth and was divided into three groups of twenty teeth each and was capped with MTA, EMD, and MTA/EMD combination. The final restoration was done with resin-modified glass ionomer cement. The teeth were then extracted on the 15th or 45th day and histological evaluation done. Results: Differences in inflammatory response and thickness of dentin bridge formation of the exposed pulp to the three different groups were statistically evaluated using Chi-square and Mann–Whitney tests and were found to be significant. No significant difference was found between MTA/EMD and MTA in terms of calcified bridge formation and pulp inflammatory response to the capping materials. Conclusions: MTA and MTA/EMD combination produced a better quality hard tissue response compared with the use of EMD.


How to cite this article:
Bollu IP, Velagula L D, Bolla N, Kumar K K, Hari A, Thumu J. Histological evaluation of mineral trioxide aggregate and enamel matrix derivative combination in direct pulp capping: An in vivo study.J Conserv Dent 2016;19:536-540


How to cite this URL:
Bollu IP, Velagula L D, Bolla N, Kumar K K, Hari A, Thumu J. Histological evaluation of mineral trioxide aggregate and enamel matrix derivative combination in direct pulp capping: An in vivo study. J Conserv Dent [serial online] 2016 [cited 2020 Aug 13 ];19:536-540
Available from: http://www.jcd.org.in/article.asp?issn=0972-0707;year=2016;volume=19;issue=6;spage=536;epage=540;aulast=Bollu;type=0