Journal of Conservative Dentistry
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ORIGINAL ARTICLE
Year : 2015  |  Volume : 18  |  Issue : 6  |  Page : 440-444

To evaluate the biocompatibility of the Indian Portland cement with potential for use in dentistry: An animal study


1 Department of Conservative Dentistry and Endodontics, KLE Society's Institute of Dental Sciences and Hospital, Bengaluru, Karnataka, India
2 Department of Conservative Dentistry and Endodontics, Krishnadevaraya College of Dental Sciences and Hospital, Bengaluru, Karnataka, India
3 Department of Oral Pathology, Krishnadevaraya College of Dental Sciences and Hospital, Bengaluru, Karnataka, India

Correspondence Address:
Dr. M G Mangala
KLE Society's Institute of Dental Sciences, No. 20, Yeshwanthpur Suburb, Second Stage, Tumkur Road, Bengaluru - 560 022, Karnataka
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0972-0707.168800

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Aims: This study evaluated the biocompatibility of the Indian Portland cement with potential for use in dentistry. Materials and Methods: This study was performed in Swiss albino mice, by implanting the Indian Portland cement pellets subcutaneously. After 1, 3, and 6 weeks the tissue specimens were prepared for histological examination. Results: The histological analysis showed moderate to severe inflammation at 1 week. The inflammation gradually decreased by 6 weeks, with most of the specimens showing the absence of inflammatory reaction. Conclusions: According to these experimental conditions, the tested Indian Portland cement was biocompatible.


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