Journal of Conservative Dentistry
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Year : 2005  |  Volume : 8  |  Issue : 4  |  Page : 4-13

An investigation into the irritant properties of some retrograde filling materials - an in vivo study

Department of Conservative Dentistry & Endodontics Dr. R. Ahmed Dental College & Hospital Kolkata, India

Correspondence Address:
Dibyendu Mazumdar
Department of Conservative Dentistry & Endodontics Dr. R. Ahmed Dental College & Hospital Kolkata
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0972-0707.42591

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This study was done to evaluate the tissue reaction to four different retrograde filling materials. In this study 60 sterile polyethylene tubes (Meditop Corporation (M) SDN. BHD., Malaysia) were divided into 5 groups of 12 tubes each. Subsequently, the first group specimens were loaded with zinc . free amalgam (Solila Nova, Dentsply), the second group specimens were loaded with Intermediate restorative material (IRM) (L.D. Caulk, Milford, DE), the third group specimens were loaded with Super EBA (Harry J. Bosworth CO, Skokie, IL) and the, fourth group specimens were loaded with Vitrebond (3M. St. Paul, MN, USA). In the last group the tubes were left empty to serve as control. 1 specimen from each group was implanted into the subcutaneous tissue of a single rabbit, making a total of 12 animals each containing an implant of every group. At the end of 2 wks, 4 wks and 12 wks the specimens along with surrounding tissues were removed from 4 rabbits. Subsequently the tissue was fixed in 10% neutral buffered formalin, embedded in paraffin, sectioned, mounted and stained using usual standard technique. The sections were examined and reaction of the soft connective tissue to the material was recorded. The data was analysed statistically.

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